| # | Children | Name | Born | Died | Father | Mother |
|---|
| 1 | | | b. 18 Apr 1820 | d. 19 Sep 1904 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 2 | | | b. 1 Apr 1822 | d. 11 Jul 1887 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 3 | | | b. 1 Apr 1824 | d. 9 Jan 1890 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 4 | | | b. 12 Sep 1826 | d. 5 Jul 1872 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 5 | | | b. 15 Apr 1829 | d. 9 Sep 1868 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 6 | | | b. 15 Jun 1831 | d. 21 Jan 1866 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 7 | | | b. 6 Mar 1834 | d. 11 Feb 1915 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 8 | | | b. 25 May 1836 | d. 5 Mar 1911 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 9 | | | b. 22 Oct 1838 | d. 1905 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 10 | | | b. 19 Jul 1841 | d. 12 Nov 1892 | Joseph William Pickens, Sr | Salina Brown Brazelton |
| 11 | | | b. 17 Jul 1845 | d. 21 Oct 1903 | Joseph William Pickens, Sr | Salina Brown Brazelton |
1804 - 1883 (79 years)