| # | Children | Name | Born | Died | Father | Mother |
|---|
| 1 | | | b. 1847 | d. 10 Jun 1923 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 2 | | | b. 1850 | d. Bef 1860 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 3 | | | b. 1851 | d. 24 Nov 1918 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 4 | | | b. 1852 | d. 23 Jul 1918 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 5 | | | b. 25 May 1854 | d. 29 Sep 1900 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 6 | | | b. 1 Mar 1857 | d. 19 Sep 1934 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 7 | | | b. 1860 | | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 8 | | | b. 9 Feb 1862 | d. 12 Dec 1917 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 9 | | | b. 1863 | d. 1904 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 10 | | | b. 25 Jul 1864 | d. 29 Nov 1912 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 11 | | | b. 1869 | d. 1885 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
| 12 | | | b. 1872 | d. 17 Nov 1941 | Henry Wilson Pickens, Sr | Lucy Wade Nowlin |
1828 - 1901 (73 years)